Viral hepatitis is associated with increased risk of decompensated cirrhosis or liver failure in patients positive for liver cytosol antibody type 1

Liver cytosol antibody type 1 (anti-LC1) is reported to be a marker of 2 autoimmune hepatitis (AIH), liver disease (AILD). However, anti-LC1 not entirely disease-specific, and its clinical value in other hepatic diseases has been well elucidated. Our study aimed explore the associations between diagnoses outcome decompensated cirrhosis or failure (DC/LF) patients positive for anti-LC1. A total 157 were included our final analysis. DC/LF was defined as The risk according diagnosis estimated using multivariable Cox proportional hazards models, while stratified regression models used subgroup analyses. found comprised various disorders. Versus diagnoses, viral associated with 2.25-fold increased these patients, independent sex, age, course, treatment drinking history. Additionally, more significant by analysis male younger non-newly diagnosed without Anti-LC1 disease-specific antibody, it multiple types disease. Furthermore, rather than AILD an These findings emphasize important role progression